These guidance articles are peer reviewed and provided to give research teams high quality and trustworthy information on how to conduct a task or resolve an issue in the design, conduct or reporting of a clinical trial. Articles are accompanied by resources, such as a template or example documents. These are free for you to download and adapt for your study. Please acknowledge www.globalhealthtrials.org if you use these.

Scoping available resources and tools used by investigators to set up and conduct malaria clinical trials in low and middle income countries within malaria endemic settings. Participate in the survey.

9th May 2017 • comment

Epidemic curves are an important component of the public health and global health toolbox. Learn more about creating and interpretting them.

9th January 2017 • comment

Become a Cochrane citizen scientist. Anyone can join their collaborative volunteer effort.

23rd December 2016 • comment
11th November 2016 • comment

Around half of the clinical trials done on medicines we use today are not published; a tragic truth that needs to be changed.

24th October 2016 • comment

A recently published paper in PLOS Medicine has investigated how adverse event data from clinical trials are summarised and consequently reported in published papers.

30th August 2016 • comment

Join us in Oxford on the 25th of April to mark World Malaria Day 2016 at a series of talks and a panel discussion. The speakers will present their latest projects and help us to understand the unique and interconnected findings of their research.

14th April 2016 • comment

Recent calls have been made for rapid and responsible sharing of research data in public health emergencies and outbreaks.

8th February 2016 • comment

Building on the concept of rapid learning health systems, Dr. Peek’s seminar focuses on the use of health information technology to address epidemiological and public health questions and to accelerate the translation of research findings to clinical practice.

22nd December 2015 • comment
22nd September 2015 • comment

Healthcare associated infections (HAI) are of important concern in patient care. This talk discusses Visual Analytics techniques which have been developed to help detect, monitor, analyse and understand trends, clusters and outbreaks of HAI.

22nd July 2015 • comment

New guidelines help researchers undertaking systematic reviews and IPD meta-analyses to report their findings in a full and transparent manner.

13th July 2015 • comment

Anders Björkman is Professor of Infectious Disease at the Karolinska Institute. In this video, Anders talks about how the efficacy of antimalarials is a major obstacle in the path towards full malaria elimination.

11th June 2015 • comment

Professor Mike English explains how KEMRI-Wellcome are ''working with government to generate patient level data from a network of Kenyan hospitals as a platform for research'.

12th May 2015 • comment

In celebration of Global Health Trials' fifth birthday (May 11th 2015) Professor Trudie Lang, Principal Investigator of the programme, talks to us about why Global Health Trials was started, why people should share their experience, and what the future holds.

8th May 2015 • comment
4th May 2015 • comment

Research ethics is strictly interrelated to scientific and methodological standards: a research project involving human participants is never ethical, if it is not scientifically and methodologically sound in the first place.

17th March 2014 • comment

An introduction into and overview on the mathematics and practice of Bayesian (adaptive) clinical trials.

31st January 2014 • comment

Researchers can often be tripped up by issues they encounter in developing regions and remote areas. Although no definitive answers are provided (there are just too many options and unknowns), the following issues should be considered when planning such a trial.  

10th May 2013 • comment

ADMIT Workshop in India

by Paritosh Malavyia, Raffaella Ravinetto, Shyam Sundar
6th May 2013 • comment

Powerpoint slides representing a comprehensive overview of some issues surrounding data management, including an overview of data management, the issue of coding, and regulations and guidelines.     NEW ADDITIONS AUGUST 2013: Code of Federal Regulations part 11 - Guidelines on how to implement

3rd April 2013 • comment

Research misconduct is a global problem as research is a global activity. Wherever there is human activity there is misconduct, but we lack reliable data on the extent and distribution of research misconduct. This PLoS paper seeks to illustrate some examples of researsch misconduct in LMICs.

3rd April 2013 • comment

In this article, the authors illustrate five basic statistical concepts that can significantly impact the interpretation of the medical literature and its application to the care of patients, drawing examples from the vaccine literature: (i) consider clinical and statistical significance separately, (ii) evaluate absolute risks rather than relative risks, (iii) examine confidence intervals rather than p values, (iv) use caution when considering isolated significant p values in the setting of multiple testing, and (v) keep in mind that statistically nonsignificant results may not exclude clinically important benefits or harms.

26th March 2013 • comment

This is a nice guidance document on principles in electronic data capture from Industry perspective (FDA)

18th March 2013 • comment

Transnational Working Group on Data management of the ECRIN, the European Clinical Research Infrastructures Network, present recommendations for quality and harmonisation for data management. In addition good data management practices in general are identified.

20th February 2013 • comment

This publication discsusses whether or not open-source clinical trial data management will improve the likelihood that good clinical trials are conducted in resource-constrained settings.

25th January 2013 • comment

A range of downloadable templates and tools for Clinical Research, including monitoring checklists, budget spreadsheets, informed consent forms, SOPs and so on.

9th August 2012 • comment

This article explains the process of data management operations within clinical trials from start to finish.

17th January 2012 • comment

An example of a academic research centre resolving the issue of clinical trial data management Peer reviewed by members of the data management expert committee for this programme.

6th October 2010 • comment

Good data management practices are essential to the success of a trial because they help to ensure that the data collected is complete and accurate. This article contains some tips to help you get started with data management.

21st November 2009 • comment