From Nature Reviews' Guide to Drug Discovery, a brilliant article by Donald A. Berry about Bayesian clinical trials.

An introduction into and overview on the mathematics and practice of Bayesian (adaptive) clinical trials. This approach is well suited to adapting to information accrueing during a trial. Within this framework there is the potential for smaller and more informative trials, and to possibly design them in a more ethical manner.

http://www.ncbi.nlm.nih.gov/pubmed/16485344

Reply

Please Sign in (or Register) to view further.