Survey launched to understand clinical and research impact of INTERGROWTH-21st tools after 170,000 downloads
by The Editorial TeamWebinar: Pregnant Women & Vaccines Against Emerging Epidemic Threats: Ethics Guidance for Preparedness, Research, and Response, 5 March 2019
by The Editorial TeamParticipatory, Action, Research: How to make your work truly participatory
by Mesh Editorial TeamEngagement Strategies: The Development of Mahidol Oxford Tropical Medicine Research Unit’s (MORU) Community and Stakeholder Engagement Strategy
by Phaik Yeong Cheah, Mesh Editorial TeamNeurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations
by INTERGROWTH-21stThe latest findings from the international INTERGROWTH-21st Project, that has monitored healthy, urban children from educated families across four continents from early pregnancy to 2 years of age, show that human neurodevelopment is not influenced by the colour of an individual’s skin.
How to Implement Blended Learning: Experiences of the Nigerian faculty
by Glory Oluwagbenga Ogunfowokan - Regional Faculty Lead, Morenike Ukpong - Senior Contributor, Regional Faculty CommitteeSeveral of Global Health Trials' Regional Faculties have implemented exceptional, cost-effective blended learning schemes, using a computer room and the Global Health Network's free eLearning courses to create a novel way of building their research teams' skills and knowledge. The Nigerian faculty explain their experiences here, and you can download their "how to" document on the right hand side of the screen, to use at your own site!
Guidelines for the Content of Statistical Analysis Plans in Clinical Trials
by Carrol Gamble, Ashma Krishan, Deborah Stocken, Steff Lewis, Edmund Juszczak, Caroline Doré, Paula Williamson, Douglas G. Altman, Alan Montgomery, Pilar Lim, Jesse Berlin, Stephen Senn, Simon Day, Yolanda Barbachano, Elizabeth LoderWhile guidance on statistical principles for clinical trials exists, there is an absence of guidance covering the required content of statistical analysis plans (SAPs) to support transparency and reproducibility. Recommendations are provided for a minimum set of items that should be addressed and included in SAPs for clinical trials. Trial registration, protocols, and statistical analysis plans are critically important in ensuring appropriate reporting of clinical trials.
ORRCA (www.orrca.org.uk) is a free, online, searchable database of research around recruitment to Clinical Trials. It aims to help users identify promising recruitment interventions and inform the matching or tailoring of these interventions to specific recruitment challenges faced by different types of trial.
Development of an online resource for recruitment research in clinical trials to organise and map current literature
by Anna Kearney, Nicola Harman, Anna Rosala-Hallas, Claire Beecher, Jane Blazeby, Peter Bower, Mike Clarke, William Cragg, Sinead Dune, Heidi Gardner, Patricia Healy, Lisa Maguire, Nicola Mills, Leila Rooshenas, Ceri Rowlands, Shaun Treweek, Akke Vellinga, Paula Williamson, Carrol GambleTransparency in the conduct and reporting of clinical trials is supported by the guidance produced on the content of clinical trial protocols and reporting standards for clinical trials. While the principle features of the statistical analysis are required within this guidance it is generally accepted that a separate Statistical Analysis Plan is also developed as the level of detail appropriate for a SAP is excessive for a protocol. However, there is no detailed guidance on the content of a SAP and consequently, there is marked variation in practice.
Global Research Nurses Skill Sharing Workshop Report: Enugu Nigeria October 11th &12th 2018
by Ekezie Ralueke OluchukwuThe workshop was attended by 120 total participants over two days, and here we provide a report of the workshop, as well as all the presentations from the day.
Performance of different clinical trial designs to evaluate treatments during an epidemic
by Matthias Brueckner, Andrew Titman, Thomas Jaki, Amanda Rojek, Peter HorbyIn the 2013-2016 west Africa outbreak of Ebola Virus Disease (EVD), most of the planned clinical trials failed to reach a conclusion within the time frame of the epidemic. We conduct a comprehensive evaluation of commonly used two- and multi-arm clinical trial designs based on real data, which was recorded during the 2013-16 EVD epidemic in west Africa
Mental Health Awareness Month
by TGHN EditorialParticipate in Doctors Without Borders (MSF) survey on the value of sharing medical case reports from humanitarian and resource limited settings
by The Editorial TeamREPORT OF THE 2018 ONE DAY FREE WORKSHOP ON CLINICAL RESEARCH CAPACITY BUILDING FOR CLINICAL RESEARCH IN NIGERIA
by Glory Oluwagbenga Ogunfowokan - Regional Faculty Lead, morenike Ukpong, AUGUSTINE ONYEAGHALA - Senior Contributor, ogundokun Olusegun - Senior Contributor, Regional Faculty Committee Member, Ekezie Ralueke OluchukwuThis report details the workshop held on 7th July 2018 at the Nigerian Airforce Conference Centre, Abuja.