SAYE: The Story of an Antimalarial Phytomedicine from Burkina Faso
by Dakuyo Zéphirin, Meda Aline Lamien, Ollo Da, Kiendrebeogo Martin, Traoré-Coulibaly Maminata, Novak Johannes, Benoit-Vical Françoise, Weisbord Emma, Willcox MerlinSPIRIT guidelines for Protocol Writing
by SPIRIT-StatementLinks to the SPIRIT guidelines for protocol development and information about these guidelines - all free and open access.
INTERGROWTH-21st Newborn Size at Birth Chart
by INTERGROWTH-21stPractical chart for health practitioners to use to assess newborn size (weight, length, head circumference) at birth against global standards. This version of the chart is being piloted within the University of Oxford hospital network, and plans to pilot in the INTERGROWTH-21st study sites and in Boston area hospitals are developing quickly. Practitioners can download and use this version of the chart freely. To connect with the INTERGROWTH-21st team regarding your experience with piloting this chart, or to request modifications to the chart (e.g. language; different institutional logo), please contact intergrowth21st@tghn.org.
Research Administration and Grant Management
by Research Administration Tools.orgLinks to resources provided by iRIM (the Initiative on Research and Innovation Management) - free online presentations and tutorials relating to how to manage grants and perform administration of clinical research projects effectively.
Managing clinical trials, of whatever size and complexity, requires efficient trial management. Trials fail because tried and tested systems handed down through apprenticeships have not been documented, evaluated or published to guide new trialists starting out in this important field.
This paper is published in BioMedCentral, with link provided in this article. Building research capacity in health services has been recognised internationally as important in order to produce a sound evidence base for decision-making in policy and practice.
TWiGH takes a look at the past year and prospects for the coming months in Ebola affected countries.
A Stronger Post-Publication Culture Is Needed for Better Science
by Hilda BastianData Safety Monitoring Boards
by C.ReddyWe repeated, 10 years apart, the retrospective treatment-outcome study on 400 children with presumed malaria in the same area (Argemone mexicana decoction).
Discussing the study protocol part 2
by D. Shamley, N.Kramer, E.Allen, L.Workman, W.Smythe, C.Ovenstone, C.ReddyWHO Global Nutrition Targets 2025: low birth weight policy brief
by INTERGROWTH-21stThis WHO policy brief is part of a series on six global nutrition targets for 2025. This brief covers the third target: a 30% reduction in low birth weight. The purpose of the brief is to increase attention to, investment in, and action for a set of cost effective interventions and policies that can help WHO Member States and their partners in reducing rates of low birth weight. INTERGROWTH-21st Chief Investigators Stephen Kennedy and Jose Villar provided expert review of these strategies, contributing the unique perspective that data from the Project, and the resulting growth standards and tools as part of overall strategies for reducing rates of low birth weight in settings across the globe. The full policy brief series can be found here: http://www.who.int/nutrition/publications/globaltargets2025_policybrief_overview/en/
Global Health Technologies Pooled Funding Webinar Summary Report
by Global Health Technologies CoalitionDiscussing the study protocol
by D. Shamley, C. Heiberg, N. Kramer, B. Wright & C. ReddyPragmatic and ethical research in disease outbreak settings: A one-day skills sharing workshop in Ghana
by Abena Konadu Yawson, Dr. Daniel Ansong, Kwaku Poku AsanteGlobal Health Trials and Kintampo Health Research Centre collaborated to run the workshop 'Pragmatic and ethical research in disease outbreaks' in November 2014. Here we provide a summary of the workshop and the presentations from the day.
The Pan African Clinical Trials Registry
by Dr Tamara Kredo of the PACTRDatabase of References for Intellectual Property Rights and Ethics
by Emma WeisbordThe INTERGROWTH-21st Project Neurodevelopment Package: A Novel Method for the Multi-Dimensional Assessment of Neurodevelopment in Pre-School Age Children
by INTERGROWTH-21stThe INTERGROWTH-21st Neurodevelopment Package is a multi-dimensional instrument measuring early childhood development (ECD). Its developmental approach may be useful to those involved in large-scale ECD research and surveillance efforts. This paper describes neurodevelopment tools for preschoolers and the systematic approach leading to the development of the Package. The Package measures vision; cortical auditory processing; and cognition, language skills, behavior, motor skills, and attention in 35-45 minutes. Sleep-wake patterns are also assessed. Tablet-based applications with integrated quality checks and automated, wireless electroencephalography make the Package easy to administer in the field by non-specialist staff. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0113360