These guidance articles are peer reviewed and provided to give research teams high quality and trustworthy information on how to conduct a task or resolve an issue in the design, conduct or reporting of a clinical trial. Articles are accompanied by resources, such as a template or example documents. These are free for you to download and adapt for your study. Please acknowledge www.globalhealthtrials.org if you use these.
Do you have research ideas for using big data to fill gender data gaps? Announcing the Big Data for Gender Challenge! Research proposals are due on July 7, 2017
Invitation to complete quick survey to improve Kaplan-Meier plots (KMunicate) ProblemThe standard way to present time-to-event data, such as survival, is with Kaplan-Meier plots. These are formatted by journals and reported in a number of ways, but we find they commonly lack some key information. The key problems are:
- Expressing how many people are contributing data at any point in the graph, including the pattern of censoring
- Expressing that the uncertainty of the estimate increases over time
Gender analysis entails researchers seeking to understand gender power relations and norms and their implications, including the nature of women’s, men’s, and people of other gender’s lives, how their needs and experiences differ, the causes and consequences of these differences, and how services and polices might address these differences.
Research Nurse Jerome Ackeneck discusses what's involved in his role on a Cameroonian HIV Study
Joby George discusses his role as a research nurse based in India; what is involved, educational oprtions available, and what's important to him.
Shared panel discussion conducted about clinical research careers in India (conducted in Telugu and English), and article about research careers in India from Sreedhar Tirunagari
Job interviews can be intimidating, but simply preparing well can make the difference between succeeding or failing, regardless of how nervous you are. In this article we pull together advice on how to prepare for job interviews and how to know what questions you’ll be asked.
Helpful, interactive eBook that aids those deciding how to further their career in research, or considernig whether to study as a post graduate.
A systematic review of barriers to and facilitators of the use of evidence by policymakers (BMC article)by Kathryn Oliver, Simon Innvar, Theo Lorenc, Jenny woodman, James Thomas
The gap between research and practice or policy is often described as a problem. To identify new barriers of and facilitators to the use of evidence by policymakers, and assess the state of research in this area, the authors present a systematic review.
Understanding the investigators: a qualitative study investigating the barriers and enablers to the implementation of local investigator-initiated clinical trials in Ethiopiaby Sam Franzen
New BMJ Open article: “Understanding the investigators: a qualitative study investigating the barriers and enablers to the implementation of local investigator-initiated clinical trials in Ethiopia” This article was written by the research team at Global Health Trials in collaboration with researchers from Ethopia, Sri Lanka and Peru. The research was initiated in response to the low volume of clinical trials conducted by investigators in Low and Middle Income Countries.
This guide, developed by the WHO and released in December 2013, aims to facilitate implementation research in LMICs.
Research misconduct is a global problem as research is a global activity. Wherever there is human activity there is misconduct, but we lack reliable data on the extent and distribution of research misconduct. This PLoS paper seeks to illustrate some examples of researsch misconduct in LMICs.
The last decade has witnessed a substantial increase of multi-centre, public health-oriented clinical trials in poor countries. However, non-commercial research groups have less staff and financial resources than traditional commercial sponsors, so the trial teams have to be creative to comply with Good Clinical Practices (GCP) requirements. This article hopes to feed the reflection on the methodological and ethical aspects of clinical trials carried out in developing countries by North-South collaborative research groups.
The border between Thailand and Burma (Myanmar) is at the forefront of the global battle against malaria, and is an important site for research.
The Critical Path to TB Drug Regimens (CPTR) Initiative is seeking new trial sites for collaboration in planned phase I and II trials. Also available in French - click on the link and scroll down for French version.
These guidelines were developed following a Working Group on Disaster Research and Ethics (WGDRE) meeting in 2007 with the aim of developing ethical guidelines which would be applicable to post-disaster research, partiuclarly that performed in the developing world. We welcome any feedback from members.