These guidance articles are peer reviewed and provided to give research teams high quality and trustworthy information on how to conduct a task or resolve an issue in the design, conduct or reporting of a clinical trial. Articles are accompanied by resources, such as a template or example documents. These are free for you to download and adapt for your study. Please acknowledge www.globalhealthtrials.org if you use these.
The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and practititionersby Carolyn A. Chew-Graham, Thomas Shepherd, Heather Burroughs, Katie Dixon, David Kessler
We report a qualitative study embedded in a trial of second antidepressant for people who had not responded to one antidepressant, exploring the acceptability of a combination of antidepressants from the perspectives of both patients and practitioners, together with experiences of participating in a clinical trial.
Protective parents and permissive children: what qualitative interviews with parents and children can tell us about the feasibility of juvenile idiopathic arthritis trialsby Frances C. Sherratt, Louise Roper, Simon R. Stones, Flora McErlane, Matthew Peak, Michael W. Beresford, Helen Foster, Athimalaipet V. Ramanan, Madeleine Rooney, Eileen Baildam, Bridget Young
Studies involving CYP are advocated in the literature but we are not aware of any early stage feasibility studies that have qualitatively accessed the perspectives of parents and CYP with a long term condition to inform design and conduct of a trial. In the context of a feasibility study to inform the design of a proposed randomised controlled trial of corticosteroid induction regimen in JIA, we explored families’ perspectives on the proposed trial and on JIA trials generally.
Nurses’ perceptions towards the delivery and feasibility of a behaviour change intervention to enhance activity in patients at risk for cardiovascular disease in primary care: a qualitative studyby Heleen Westland, Yvonne Koop, Carin D. Schröder, Marieke J. Schuurmans, P. Slabbers, Jaap C. A. Trappenburg, Sigrid C. J. M. Vervoort
This study aimed to evaluate nurses’ perceptions towards the delivery and feasibility of the Activate intervention.
Including qualitative research in Randomized Controlled Trials (RCT): opportunities for nursing researchersby Loredana Sasso, Mark Hayter, Gianluca Catania, Giuseppe Aleo, Milko P Zanini , Annamaria Bagnasco
n this editorial we argue that qualitative research can enhance the quality, rigor and depth of an RCT –but at present this is an opportunity that is frequently missed. We further propose that not only can qualitative research enhance the design and conduct of an RCT it also provides an opportunity for qualitative researchers (often nurse researchers) and research nurses (often not actively involved in undertaking research) to work with medical colleagues to improve the quality of RCT design.
This page provides links to commonly used reporting guidelines for qualitative research, as well as articles which provide useful information about how to write about your research.
This paper provides a general guide to presenting qualitative research for publication in a way that has meaning for authors and readers, is acceptable to editors and reviewers, and meets criteria for high standards of qualitative research reporting across the board. We discuss the writing of all sections of an article, placing particular emphasis on how you might best present your findings, illustrating our points with examples drawn from previous issues of this Journal.
Knowledge and attitude towards Ebola and Marburg virus diseases in Uganda using quantitative and participatory epidemiology techniquesby Luke Nyakarahuka, Eystein Skjerve, Daisy Nabadda, Doreen Chilolo Sitali, Chisoni Mumba, Frank N. Mwiine5, Julius J. Lutwama, Stephen Balinandi, Trevor Shoemaker, Clovice Kankya
Useful paper which uses mixed qualitative and quantitative methods to consider knowledge and practices around ebola and marburg virus in Uganda
Unintended consequences of the ‘bushmeat ban’ in West Africa during the 2013–2016 Ebola virus disease epidemicby Jesse Bonwitt, Michael Dawson, Martin Kandeh, Rashid Ansumana, Foday Sahr, Hannah Brown, Ann H. Kelly
This interesting article uses qualitative research to consider the impacts of the bushmeat ban, and consider whether illegalising bushmeat had the desired effect. Useful, interesting paper for anyone with an interest in the ebola virus and how to encourage behaviour change.
Conducting good, ethical global health research is now more important than ever. Increased global mobility and connectivity mean that in today’s world there is no such thing as ‘local health’. As a collection, these stories offer a flexible resource for training across a variety of contexts, such as medical research organizations, universities, collaborative sites, and NGOs.
This helpful NIHR toolkit provides a comprehensive guide to the stages of designing and planning, carrying out, and reporting on a qualitative study, and includes useful exercises. We recommend it to anyone needing a useful, broad guide.
Assessing quality in qualitative research can be very different to other research types. Here we have compiled some resources which may help to assess the quality of research in different ways.
There are many different approaches to analysing qualitative data. This article aims to bring together resources and articles around some of the more common types of analysis, so that you can easily find what you need.
Useful videos about conducting focus groups for qualitative research
Useful YouTube videos about conducting qualitative research interviews
Gender analysis entails researchers seeking to understand gender power relations and norms and their implications, including the nature of women’s, men’s, and people of other gender’s lives, how their needs and experiences differ, the causes and consequences of these differences, and how services and polices might address these differences.
Social science guidance from the ACT Consortium available for wider research community, including training materials, SOPs, template protoclos and other tools.
Quality assurance of qualitative research: a suggested approach for assessing and strengthening qualitative research within global health trialsby Joanna Reynolds, Susan Naiga, Lilian Taaka, Clare I. R. Chandler
The ACT consortium have developed and piloted an approach through which qualitative research activities can be assessed and strengthened: the ‘quality assessment and strengthening’ (QAS) approach. This article explains the QAS approach and gives an example protocol.