Performance of different clinical trial designs to evaluate treatments during an epidemic
by Matthias Brueckner, Andrew Titman, Thomas Jaki, Amanda Rojek, Peter HorbyIn the 2013-2016 west Africa outbreak of Ebola Virus Disease (EVD), most of the planned clinical trials failed to reach a conclusion within the time frame of the epidemic. We conduct a comprehensive evaluation of commonly used two- and multi-arm clinical trial designs based on real data, which was recorded during the 2013-16 EVD epidemic in west Africa
17th October 2018 •
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