Bookmarks
World TB Day 2012: Strengthening tuberculosis research in AfricaOn the occasion of World Tuberculosis (TB) Day, 24 March 2012, the European and Developing Countries Clinical Trials Partnership (EDCTP) has published a short video that highlights some of the EDCTP funded TB research in sub-Saharan Africa. In addition, this article presents several areas of development: new diagnostic tools, shorter treatment periods, prevention of TB, and safe treatment combinations in TB-HIV co-infected patients.
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Identification of a predominant genotype of Mycobacterium tuberculosis in Brazilian indigenous population
by S. A. Hadi et al.After nearly a century of vaccination and six decades of drug therapy, tuberculosis (TB) kills more people annually than any other infectious disease. Substantial challenges to disease eradication remain among vulnerable and underserved populations. The Guarani-Kaiowá people are an indigenous population in Paraguay and the Brazilian state of Mato Grosso do Sul. This community, marginalized in Brazilian society, experiences severe poverty.
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain
by Vegard Eldholm et alEffects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africa
by Nomonde R Dlamini-Mvelase, Lise Werner, Rogerio Phili, Lindiwe P Cele and Koleka P MlisanaRapid and Inexpensive Detection of MDR Mycobacterium tuberculosis using a Resazurin Microtitreplate Assay in a High Burden Tuberculosis Reference Laboratory
by Prenika Jaglal, Melendhran Pillay, Koleka MlisanaNew publication on rifampicin Mono-Resistance in TB
by Yacoob Mahomed Coovadia, Sharana Mahomed, Melendhran Pillay, Lise Werner, Koleka MlisanaMobile Phone Based Clinical Microscopy for Global Health Applications
by David N. Breslauer, Robi N. Maamari, Neil A. Switz, Wilbur A. Lam, Daniel A. FletcherDirect susceptibility testing for multi drug resistant tuberculosis: a meta-analysis
by Freddie Bwanga, Sven Hoffner, Melles Haile, Moses L JolobaAlternative methods of diagnosing drug resistance - What can they do for me?
by David AJ Moore, N Sarita ShahPromise versus Reality: Optimism Bias in Package Inserts for Tuberculosis Diagnostics
by Claudia M. Denkinger, Jasmine Grenier, Jessica Minion, Madhukar PaiThis review, written by Ruth McNerney and Peter Daley, provides an overview of the state of research into point-of-care diagnostics for active tuberculosis and highlights the barriers to the development of these tests.
Improving the Diagnostic Ecosystem: A Critical Step in Controlling the TB Epidemic in India and Globally
by Madhukar PaiPoint-of-Care Diagnostics for HIV and Tuberculosis: Landscape, Pipeline, and Unmet Needs
by Nitika Pant Pai, Madhukar PaiComing soon! A paper series on clinical trial design for tropical diseases. Read more here and get involved!