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Our experience with OpenClinica

Performing clinical trials in resource-constrained settings requires an affordable and easy to use data management system that is compliant with applicable standards. It is a bold step to adopt a web-based system in a large multi-site clinical trial in an area with challenging communication infrastructure. The process has been successful but not without its challenges. In this presentation, we look at the experience in setting up and use of OpenClinica in Africa with a case study on a large multi-site clinical trial in East Africa that has adopted OpenClinica. The presentation describes the difficulties faced, approaches taken to counter the challenges and best practices adopted. We also propose additional functionality that we believe would make the system more useful in such settings.

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Bookmarked by Naomi Waithira on 14 Jun 2010
3 points

free online health courses

USAID's Global Health eLearning Center announcinga the release of four new courses:

Cervical Cancer Prevention (Low-Resource Settings)
Gender and Reproductive Health 101
Commercial Private Health Sector Basics
Antimicrobial Resistance Part I

Please have a look at these and post your feedback on their broad relevance and interest. We are keen to see how helpful they are do those conducting research in resource limited settings.

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Bookmarked by The Editorial Team on 19 Jun 2010
2 points

The Pan African Clinical Trials Registry (PACTR)

The Pan African Clinical Trials Registry (PACTR) is a regional register of clinical trials conducted in Africa. The registry is an African initiative serving the needs of Africans. It provides a platform where clinical trials can be registered prospectively. In addition, it also provides a searchable, electronic database of planned trials and trials currently in progress. The PACTR is unique in recognising that African trialists face additional challenges in trial registration and seeks to provide feasible ways of overcoming these. For example, a common problem for individuals living in sub-Saharan Africa is limited, unreliable and costly internet access. With this in mind, the registry provides alternative means of trial registration for registrants who do not have reliable access to the internet. Trials may be registered manually by email, postal mail or facsimile correspondence and trial registration is free.

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Bookmarked by Andy Burke on 25 Jun 2010
1 point

Free online Biostatistics and Laboratory Techniques courses offering certificate

Introduction to Biostatistics provides an introduction to selected important topics in biostatistical concepts and reasoning through lectures, exercises, and bulletin board discussions. This course represents an introduction to the field and provides a survey of data and data types. Specific topics include tools for describing central tendency and variability
in data; methods for performing inference on population means and proportions via sample data; statistical hypothesis testing and its application to group comparisons; issues of power and sample size in study designs; and random sample and other study types. While there are some formulae and computational elements to the course, the emphasis is on interpretation and concepts.

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Bookmarked by Sam Franzen on 28 Jun 2010
3 points

Support for health systems research

Practihc (Pragmatic Randomized Controlled Trials in HealthCare) is a European Union-funded converted action which provides open-access tools, training and mentoring to researchers in developing countries who are interested in designing and conducting pragmatic randomized controlled trials of healthcare interventions.
Practihc is a collaboration of leading trialists from eleven countries who aim to improve health systems by increasing capacity to evaluate healthcare delivery systems, health policy, public health and clinical choices an identify those optoins which are most effective.

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Bookmarked by The Editorial Team on 13 Jul 2010
1 point