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Conducting research in resource limited settings can be challenging. Global Health Trials (GHT) is one resource that reaches even the remotest of the resource limited settings for as long as one has internet connectivity. Mbale Regional Referral Hospital is a site with a high burden of a wide spectrum of African tropical infectious diseases and therefore research on such diseases is easy in terms of availability of target population. However we have very limited access to computers and fast internet connectivity. To keep my research staff up dated on clinical research including trials, I have decided to have a central facility (Two computers connected to reliable internet) so they can access this useful learning and training tool. I am personally impressed by the efforts by GHT and they have given me the training resources and strengthened my leadership skills in upgrading my site to a clinical trials site. Thank you GHT!
Peter Olupot-Olupot
Site Principal Investigator

  • fridao Frida OYAKHIROMEN 23 Nov 2011

    Thank you for your feedback dear Peter as this is what we all need to know to even do more than we are right now, so dear researchers, please do contribute with your input, experience, documents for a further advancement of research in Africa....

  • fridao Frida OYAKHIROMEN 23 Nov 2011

    Thank you for your feedback dear Peter as this is what we all need to know to even do more than we are right now, so dear researchers, please do contribute with your input, experience, documents for a further advancement of research in Africa....

  • IMPROVED RESEARCH ETHICS REVIEW PROCESS FOR STUDIES DONE ACROSS THE NATIONS.

    Often times, we receive proposals from researchers from the Western World requesting for ethical approval of a studies that have either a component in Western World as well as Uganda or Researcher in Western World wanting to do research in Uganda. Research protocols falling in either setting need clearance from both the researcher's institution in the Western Country and Uganda. In the process the researcher goes through ethical review process in the home institution, then starts the process all over again in Uganda. Whereas, we all need certainty of safety and autonomy of the research participants and to be sure that the investigator is qualified and has presented a scientifically sound protocol, the process of research ethics review in two countries is a very demanding process, often involving a lot of time (delay in execution of the study), tiring for the researcher and often duplicates the process.One way we are starting to view the way forward is to have Dual application and review process. This means, the researcher presents the request for review to both our IRB as well as the home institution IRB at the same time. However, the researcher links the two IRBs so that they sort out ethical issues together. By the time the IRBs come to the researcher, the latter has a final position from both IRBs. This in addition would promote networking, capacity building, sharing of resources, bridges the gap that may exist between the IRBs in the two settings and promotes research.
    However, we anticipate some problems due to electronic/technological development differences, confidentiality issues and archival of research information.
    We hope to pilot this idea, we welcome ideas, comments and contributions to shape this project.

    MRHIRC, Mbale, Uganda.

  • dkamuya Dorcas Kamuya 14 Feb 2012

    Interesting approach to multinational/collaborative research review, there is a wealth of literature on this area. While efforts to ensure scientifically valid and ethically appropriate research is conducted, there cautions against some of the approaches; including perceived abdication of researcher responsibility when they are far removed from the review proposes, IRBs significantly changing the research, and role of host IRB etc. Really looking forward to hear more about how this works in practice. I will post some references around this area later.