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Grupo de Investigación en Sueño - Perú
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Bookmarked by Edmundo Rosales-Mayor on 21 Jul 2010
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MRC call for African Leaders funding opportunityPlease see think link for a call the the UK's Medical Research Council have release to support the development of African research leaders.
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Bookmarked by Trudie Lang on 20 Jul 2011
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eMagazine for those with an interest in Global Health Research
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Bookmarked by The Editorial Team on 18 Aug 2011
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International TB Research Roadmap Launched!A plan targeting researchers around the world and providing them with a framework to achieve the research objectives of the the Global Plan to Stop TB 2011-2015 and beyond, towards elimination of TB, was launched on Saturday at the Union World Conference on Lung Health.
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Bookmarked by The Editorial Team on 15 Nov 2011
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Identifying Research Priorities in Musculoskeletal Trauma Care in Sub-Saharan Africa
by Orthopaedic Research Collaboration AfricaA consensus-based approach to identify research priorities for clinical trials and research in musculoskeletal trauma care across sub-Saharan Africa.
Reboot biomedical R&D in the global public interest
by Soumya Swaminathan et al.Inequitable access to the fruits of research during the COVID-19 pandemic highlights the urgency — and feasibility — of overhauling the R&D system.
Ralueke Ekezie is an innovative research nurse in Nigeria, and a long-standing member of Global Health Trials and Global Research Nurses. He has organised many events to support research nurses in Nigeria. Here, he tells us about his role.
The number of publications about dengue fever has grown strongly since 1960 reflecting strong growth in the number of global cases.
Study of volunteer blood donors in Martinique provides new information about Zika virus infection
by ISARICThis pioneering study provides a precise follow-up of incident cases and seroprevalence in blood donors, and it also provides important insights into the management of blood donations during ZIKV outbreaks and into the natural history of ZIKV infection in adults. It suggests that the study of blood donors during outbreaks of emerging pathogens has become a key element of epidemiological surveillance.
A study performed by the Institut National de la Santé et de la Recherche Médicale (INSERM) team of Dr Ali Amara (U944, Paris, France) and published in Cell Reports sheds new light on the mechanisms allowing ZIKV to infect cells within the human nervous system. Amara et al. showed that the protein Axl is expressed in a number of brain glial cells and that the entry of ZIKV into these cells requires another protein, Gas6, to act as a bridge between the ZIKV particles and the glial cells.
Zika virus in asymptomatic blood donors in Martinique
by Gallian et al.This pioneering study suggests that the study of blood donors during outbreaks of emerging pathogens has become a key element of epidemiological surveillance.
A study performed by the Institut National de la Santé et de la Recherche Médicale (INSERM) team of Dr Ali Amara (U944, Paris, France) and published in Cell Reports sheds new light on the mechanisms allowing ZIKV to infect cells within the human nervous system. Amara et al. showed that the protein Axl is expressed in a number of brain glial cells and that the entry of ZIKV into these cells requires another protein, Gas6, to act as a bridge between the ZIKV particles and the glial cells.
By using the bacterium-free ‘Infectious Subgenomic Amplicons’ (ISA) method, this study provides the scientific community with two simple and performing reverse genetics systems for ZIKV.
Clinical trial for experimental Ebola drug publishes results
by ERGO Editorial TeamWith video. Results of the Wellcome Trust funded trial of the experimental anti-Ebola drug TKM-130803 have been published in PLoS Medicine. Using a novel approach designed to get rapid indications of a drug’s effectiveness, the trial showed that at the dose given the drug did not improve survival compared to historic controls.
Become a CoLab Member
by Global Pregnancy CoLabWHAT IS THE GLOBAL PREGNANCY COLLABORATION (COLAB)? CoLab is a consortium of international investigative groups with data and biological samples from women prior to, during and in some cases, long after an adverse pregnancy outcome. These data and samples are in a membership-wide shared database and available to CoLab members and to investigators sponsored by CoLab members. We currently have members from over 35 centers with more than 300,000 pregnancies and we are growing! We believe the time has come in obstetrical research to pool research and intellectual resources to begin to address and answer questions that could not otherwise be answered by a single investigative group.
How to Get Data and/or Biological Samples
by Global Pregnancy CoLabHOW TO COLLABORATE? Applicants with research interests relevant to CoLab (complications of pregnancy) may apply to collaborate with CoLab. Please note that to obtain samples and/or data from CoLab cohorts, you will need a member of CoLab to be your sponsor. We can help assist you in getting a sponsor. All CoLab projects are considered collaborations and you will work directly with CoLab members and cohorts to obtain data and/or biological samples for your project. However, you will work directly with the CoLab office thorough the application process, to give quarterly updates, and to work with a protocol committee regarding your project.
Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal Domain
by James R. Carter, Samantha Taylor, Tresa S. Fraser, Cheryl A. Kucharski, James L. Dawson, Malcolm J.Research points to a promising single antiviral for the transgenic suppression of multiple arboviruses
Could a protein be key to new dengue drug discoveries?
by Gary FinneganScientists belive a protein may be key to new dengue drug discoveries?
The Critical Path to TB Drug Regimens (CPTR) Initiative is seeking new trial sites for collaboration in planned phase I and II trials. Also available in French - click on the link and scroll down for French version.
The Draft Statement/Guidelines for Disaster Research
by Arthula Sumathipala, Aamir Jafarey, Leonardo de Castro, Aasim Ahmad, Darryl Marcer, Sandya Srinivasan, Nandini K. Kumar, Slemen Sutaryo, Anant Bhan, Dananyaja Wadeyaratne, Sriyakanthi Beneragama, Chandrani Jayasekera, Sarath Edirisingha, Chesmal Siriwardhana, Sisira SiribaddanaThese guidelines were developed following a Working Group on Disaster Research and Ethics (WGDRE) meeting in 2007 with the aim of developing ethical guidelines which would be applicable to post-disaster research, partiuclarly that performed in the developing world. We welcome any feedback from members.