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The course is jointly organised by the Jenner Institute, the International Livestock Research Institute (ILRI), and the Fondation Mérieux, with financial support from the Jenner Vaccine Foundation, Fondation Mérieux, GSK, and other funders. The first ‘Vaccinology in Africa’ course was successfully conducted in Accra, Ghana, in September 2013, and received excellent feedback from the 30 course participants from the West African region, as well as from speakers and funders. This year 30 students from East Africa are expected to participate, with a faculty of around 15 international lecturers drawn from the Oxford Vaccinology Course and the Fondation Mérieux’s ADVAC course, as well as prominent African vaccine experts. The course will be covering the main aspects of vaccinology, the vaccine development process, biomanufacturing and well as regulatory and ethical issues. The course is aimed at students, researchers and professionals resident in East Africa. Delegate numbers will be limited to 30 participants. How to apply Participation is competitive and places are allocated based on individual applications. 15 places are available for local residents of Kenya which will cover course fees, accommodation and meals during the course. A further 15 bursaries are available for those living further afield within the region of East Africa which will also include travel expenses. Application deadline is 1st June 2014. To download an application form, please visit http://www.jenner.ac.uk/vaccinology-in-africa and download the relevant form. To apply and for all enquiries, please email: jenner-applications@ndm.ox.ac.uk Confirmed Speakers Prof Dicky Akanmori, WHO Regional Office for Africa Prof Brigitte Autran, INSERM Dr Philip Bejon, Oxford/KEMRI Prof Ogobara Doumbo, MRTC, Bamako Dr Bryan Charleston, Pirbright Dr Helen Fletcher, LSHTM Prof Sarah Gilbert, Oxford Prof Giuseppe del Giudice, Novartis, Siena Prof Sir Brian Greenwood, LSHTM Dr Karin Hardt, GSK Prof Adrian Hill, Oxford Prof David Lewis, Surrey Prof Kevin Marsh, KEMRI Prof Helen McShane, Oxford Dr Vasee Moorthy, WHO Dr Vish Nene, ILRI Dr Bernhards Ogutu, KEMRI Prof David Salisbury, Jenner Vaccine Foundation Dr Geraldine Taylor, Pirbright Preliminary Programme: Day 1: Principles of Vaccinology • Overview of human and veterinary vaccinology - A Hill • Public health and vaccines: a WHO perspective - V Moorthy • The vaccine development pathway – an industry perspective - K Hardt • Vaccine immunology - H Fletcher • Vaccines: needs and opportunities - D Akanmori • Policy development and new vaccine introduction - D Salisbury Day 2: Vaccine technologies & their development • Vaccine immunogenicity & correlates of protection in clinical trials - A Hill • Adjuvants for vaccines - K Hardt • New technologies: vectored vaccines - A Hill • Conjugate and other pneumococcal vaccines - B Greenwood • Reverse vaccinology for meningococcal vaccines - G del Giudice • Public and media perception of vaccines - D Salisbury • Workshop on vaccine design - H Fletcher/G Taylor Day 3: Major Vaccine Targets • Malaria vaccines - A Hill • Tuberculosis vaccine trials - H McShane • Men-A conjugate: a vaccine for Africa - B Greenwood • Vaccines for enteric pathogens - D Lewis • Veterinary vaccine development: some major needs - B Charleston • PPR and RSV vaccines - G Taylor • Foot and mouth disease vaccines - B Charleston • Immunomonitoring in endemic areas – tutorial session - H Fletcher/G Taylor Day 4: Vaccine Development and Clinical Trials • Phase I trials in the vaccine’s country of origin - B Autran • Vaccine testing in semi-immune populations - O Doumbo • Good Clinical Practice in African trials - B Ogutu • Epidemiology and aspects of the design of vaccine field trials - P Bejon • Safety considerations in the conduct of clinical trials of candidate vaccines - EB Imoukhuede • QC and QA processes in vaccine trials - K Hardt • HIV vaccine trials - B Autran • Influenza vaccines - S Gilbert Day 5: Vaccine Development in Developing Countries • Vaccine manufacturing - S Gilbert • Pre-clinical studies to Phase I clinical trials in developing countries - O Doumbo • Veterinary vaccine development in African settings - V Nene • Large scale intervention trials - K Marsh • Statistical analysis of vaccine trials - P Bejon • Regulatory and ethical issues in vaccine development & deployment in African settings - D Akanmori • Large scale funding opportunities: EDCTP, Gates, Wellcome & others - D Akanmori