ARTICLE ABSTRACT
Sharing clinical trial data is critical in order to inform clinical and regulatory decision making and honor trial participants who put themselves at risk to advance science. A recent Institute of Medicine (IOM) report argues that availability of deidentified (anonymized) patient-level data from clinical trials can permit verification of original results, enhancing public trust and accountability; facilitate other critical research (e.g., evaluation of adverse event rates according to compound class or subpopulation or identification of surrogate end points); and avert duplicate trials, shielding participants from unnecessary risk.1 If such goals are to be achieved, patient-level data must be readily findable and available for aggregation and analysis across multiple sources to enable the widest range of secondary research uses.
Brigham and Women's Hospital–Harvard University's Multi-Regional Clinical Trials Center, along with partners, is designing a platform to link existing data-sharing platforms and communities and host data from investigators who want to share data but lack the resources to do so.
Link to access full article: www.nejm.org/doi/10.1056/NEJMp1605348
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